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Caffeine intake by patients with autosomal dominant polycystic kidney disease

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dc.contributor.author Vendramini, L.C.
dc.contributor.author Nishiura, J.L.
dc.contributor.author Baxmann, A.C.
dc.contributor.author Heilberg, I.P.
dc.date.accessioned 2022-06-30T18:25:13Z
dc.date.available 2022-06-30T18:25:13Z
dc.date.issued 2012
dc.identifier.citation VENDRAMINI, L. C. et al. Caffeine intake by patients with autosomal dominant polycystic kidney disease. Brazilian Journal of Medical and Biological Research, Ribeirão Preto, v. 45, n. 9, p. 834-840, set. 2012. pt_BR
dc.identifier.issn 1414-431X
dc.identifier.uri https://doi.org/10.1590/S0100-879X2012007500120 pt_BR
dc.identifier.uri http://www.sbicafe.ufv.br/handle/123456789/13566
dc.description.abstract Because caffeine may induce cyst and kidney enlargement in autosomal dominant polycystic kidney disease (ADPKD), we evaluated caffeine intake and renal volume using renal ultrasound in ADPKD patients. Caffeine intake was estimated by the average of 24-h dietary recalls obtained on 3 nonconsecutive days in 102 ADPKD patients (68 females, 34 males; 39 ± 12 years) and compared to that of 102 healthy volunteers (74 females, 28 males; 38 ± 14 years). The awareness of the need for caffeine restriction was assessed. Clinical and laboratory data were obtained from the medical records of the patients. Mean caffeine intake was significantly lower in ADPKD patients versus controls (86 vs 134 mg/day), and 63% of the ADPKD patients had been previously aware of caffeine restriction. Caffeine intake did not correlate with renal volume in ADPKD patients. There were no significant differences between the renal volumes of patients in the highest and lowest tertiles of caffeine consumption. Finally, age-adjusted multiple linear regression revealed that renal volume was associated with hypertension, chronic kidney disease stage 3 and the time since diagnosis, but not with caffeine intake. The present small cross-sectional study indicated a low level of caffeine consumption by ADPKD patients when compared to healthy volunteers, which was most likely due to prior awareness of the need for caffeine restriction. Within the range of caffeine intake observed by ADPKD patients in this study (0-471 mg/day), the renal volume was not directly associated with caffeine intake. pt_BR
dc.format pdf pt_BR
dc.language.iso en pt_BR
dc.publisher Associação Brasileira de Divulgação Científica pt_BR
dc.relation.ispartofseries Brazilian Journal of Medical and Biological Research;v.45, n.9, 2012
dc.rights Open Access pt_BR
dc.rights.uri Open Access pt_BR
dc.subject Polycystic kidneys pt_BR
dc.subject ADPKD pt_BR
dc.subject Cyclic AMP pt_BR
dc.subject Caffeine pt_BR
dc.subject Nutrition pt_BR
dc.subject Renal volume pt_BR
dc.subject.classification Cafeicultura::Café e saúde pt_BR
dc.title Caffeine intake by patients with autosomal dominant polycystic kidney disease pt_BR
dc.type Artigo pt_BR

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